That legal trouble was owed to the major ingredient in Roundup: glyphosate. This chemical, whose toxicity made Roundup so effective, became publicly connected to both human illness and environmental damage.
The first major salvo came when the International Agency for Research on Cancer published research in 2015 indicating that glyphosate was “probably carcinogenic to humans.” While this was not the first study to connect glyphosate to cancer, it was by far the most prominent to date and touched off an international uproar.
The herbicide's reputation has come under increasingly fierce attacks since, with 2018 being a major turning point.
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